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The Burden Of Treatment Resistance In MDD

janssen -spravato
5_3.

BDNF, Brain-derived neurotrophic factor. AMPA, α-amino-3-hydroxy-5- methyl-4-isoxazolepropionic acid. GABA, gamma-aminobutyric acid. NDMA, N-methyl-D-aspartate.

References:
1- Spravato Summary of Product Characteristics. https://www.ema.europa. eu/en/documents/product-information/spravato-epar-product-information_ en.pdf. Last Accessed 03.01.2021
2- Duman RS, Aghajanian GK, Sanacora G, Krystal JH. Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants. Nat Med . 2016; 22 (3) :238-49.

CP-225221