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OPSUMIT IMPROVES FUNCTIONAL AND HAEMODYNAMIC PARAMETERS WHEN USED IN EARLY COMBINATION THERAPY1

Initial double combination therapy with OPSUMIT and tadalafil led to significant improvements from baseline to Week 16 in cardiopulmonary haemodynamics (except reduction in mRAP is non-significant ), functional parameters, NT-proBNP and risk profile in newly diagnosed, treatment-naïve patients with PAH.1

References:

[1] Sibton O, Cottin V, Canuet M, et al. initial combination therapy of macitentan and tadalafil in pulmonary arterial hypertension. Eur Respir J. 2020 Sep 3;56 (3):2000673.

[2] OPSUMIT SmPC, April 2020. Available at: https://www.ema.europa.eu/en/d... en.pdf (last accessed October 2020).

[3] OPSUMIT Ministry of health approved leaflet 15/10/2018

CP-263136