aAs measured by a composite primary endpoint. Results were driven by a decrease in PAH worsening and do not apply to
mortality on its own. bEvents defined as composite morbidity-mortality events.
PAH: Pulmonary arterial hypertension
2. OPSUMIT Summary of Product Characteristics. Available at: https://www.ema.europa.eu/en
/documents/productinformation/opsumit-epar-product-information_en.pdf. Last accessed: November 28, 2019.